Yes, of course! I was just surprised when I moved from setting type to tutoring readers that all that structure I was subtly encoding wasn't escaping into the reader's experience.

Were you reading a commercial e-book? Were any typographic structural info discernable? Are Bookshare.org's products HTML or flat text? And for the last flurry in this question: how do you set your voices to distinguish between plain, italic, and bold?